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STEAP1 Polyclonal Antibody

     
  • 1 - STEAP1 Polyclonal Antibody AP72640
    Western Blot analysis of various cells using STEAP1 Polyclonal Antibody
  • 14 - STEAP1 Polyclonal Antibody AP72640
    Immunohistochemical analysis of paraffin-embedded Human prostate cancer. Antibody was diluted at 1:100(4°,overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P
Primary Accession Q9UHE8
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 39851 Da
Additional Information
Gene ID 26872
Other Names STEAP1; PRSS24; STEAP; Metalloreductase STEAP1; Six-transmembrane epithelial antigen of prostate 1
Dilution WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
IHC-P~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name STEAP1
Synonyms PRSS24, STEAP
Function Does not function as a metalloreductase due to the absence of binding sites for the electron-donating substrate NADPH. Promotes Fe(3+) reduction when fused to the NADPH-binding domain of STEAP4.
Cellular Location Endosome membrane {ECO:0000250|UniProtKB:Q9CWR7}; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Tissue Location Ubiquitously expressed. Highly expressed in prostate tumors.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.

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