癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
DANRE pax2a Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q90268 |
| Reactivity | Zebrafish |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 44099 Da |
| Antigen Region | 258-284 aa |
| Gene ID | 30425 |
|---|---|
| Other Names | Paired box protein Pax-2a, No isthmus protein, Pax[Zf-b], pax2a, noi, pax21, paxzf-b |
| Target/Specificity | This DANRE pax2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-284 amino acids from the Central region of DANRE pax2a. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DANRE pax2a Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | pax2a |
|---|---|
| Synonyms | noi, pax2.1, paxzf-b |
| Function | Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation. |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed during embryogenesis in the kidney, optic stalk, midbrain, otic vesicle and a row of cells along the spinal cord and the hindbrain |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation.
REFERENCES
Krauss S., et al. Development 113:1193-1206(1991).
Lun K., et al. Development 125:3049-3062(1998).
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