ALDH6A1 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| IF, IHC-P, WB |
---|---|
Primary Accession | Q02252 |
Reactivity | Human |
Predicted | Mouse |
Host | Mouse |
Clonality | Monoclonal |
Calculated MW | 57840 Da |
Isotype | IgG1,κ |
Antigen Source | HUMAN |
Gene ID | 4329 |
---|---|
Antigen Region | 104-523 aa |
Other Names | ALDH6A1; MMSDH; Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Aldehyde dehydrogenase family 6 member A1 |
Dilution | IF~~1:25 IHC-P~~1:100~500 WB~~1:1000 |
Target/Specificity | This ALDH6A1 antibody is generated from mouse immunized with ALDH6A1 recombinant protein. |
Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ALDH6A1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ALDH6A1 (HGNC:7179) |
---|---|
Function | Malonate and methylmalonate semialdehyde dehydrogenase involved in the catabolism of valine, thymine, and compounds catabolized by way of beta-alanine, including uracil and cytidine. |
Cellular Location | Mitochondrion. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
REFERENCES
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. Saito A, et al. J Hum Genet, 2009 Jun. PMID 19343046.
Physical mapping of CHX10, ALDH6A1, and ABCD4 on bovine chromosome 10q34. Kuiper H, et al. Cytogenet Genome Res, 2005. PMID 15909363.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
The human plasma proteome: a nonredundant list developed by combination of four separate sources. Anderson NL, et al. Mol Cell Proteomics, 2004 Apr. PMID 14718574.

终于等到您。ABCEPTA(百远生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问,联系:0512-88856768 tech-china@abcepta.com.