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>   首页   >   产品   >   一抗   >   基因重组   >   Anti-CALCA / CGRP Reference Antibody (fremanezumab)   

Anti-CALCA / CGRP Reference Antibody (fremanezumab)

Recombinant Antibody

     
  • 1 - Anti-CALCA / CGRP Reference Antibody (fremanezumab) APR10725
    Anti-CALCA / CGRP Reference Antibody (fremanezumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
  • 1 - Anti-CALCA / CGRP Reference Antibody (fremanezumab) APR10725
    The purity of Anti-CALCA / CGRP Reference Antibody (fremanezumab)is more than 100% ,determined by SEC-HPLC.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
FC, Kinetics, Animal Model
Primary Accession P06881
Reactivity Human
Clonality Monoclonal
Isotype IgG2SA
Calculated MW 13899 Da
Additional Information
Target/Specificity CALCA / CGRP
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Protein Information
Name CALCA (HGNC:1437)
Synonyms CALC1
Function CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex (PubMed:1318039, PubMed:33602864, PubMed:9620797). Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role (PubMed:3492492). It also elevates platelet cAMP (PubMed:1318039). CGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex (PubMed:38603770).
Cellular Location Secreted.
Tissue Location Expressed in spinal cord.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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