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>   首页   >   产品   >   一抗   >   基因重组   >   Anti-EphA3 Reference Antibody (ifabotuzumab)   

Anti-EphA3 Reference Antibody (ifabotuzumab)

Recombinant Antibody

     
  • 1 - Anti-EphA3 Reference Antibody (ifabotuzumab) APR10514
    Anti-EphA3 Reference Antibody (ifabotuzumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
  • 1 - Anti-EphA3 Reference Antibody (ifabotuzumab) APR10514
    The purity of Anti-EphA3 Reference Antibody (ifabotuzumab)is more than 95% ,determined by SEC-HPLC.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
FC, Kinetics, Animal Model
Primary Accession P29320
Reactivity Human, Mouse
Clonality Monoclonal
Isotype IgG1
Calculated MW 110131 Da
Additional Information
Target/Specificity EphA3
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Protein Information
Name EPHA3
Synonyms ETK, ETK1, HEK, TYRO4
Function Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in cardiac cells migration and differentiation and regulates the formation of the atrioventricular canal and septum during development probably through activation by EFNA1. Involved in the retinotectal mapping of neurons. May also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.
Cellular Location [Isoform 1]: Cell membrane; Single-pass type I membrane protein
Tissue Location Widely expressed. Highest level in placenta.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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