注册 | 登录
点击这里给我发消息
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   一抗   >   基因重组   >   Anti-ROR1 Reference Antibody (zilovertamab)   

Anti-ROR1 Reference Antibody (zilovertamab)

Recombinant Antibody

     
  • 1 - Anti-ROR1 Reference Antibody (zilovertamab) APR10206
    Anti-ROR1 Reference Antibody (zilovertamab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
  • 1 - Anti-ROR1 Reference Antibody (zilovertamab) APR10206
    The purity of Anti-ROR1 Reference Antibody (zilovertamab)is more than 98.21% ,determined by SEC-HPLC.
  • 1 - Anti-ROR1 Reference Antibody (zilovertamab) APR10206
    Immobilized human ROR1 His at 2  µg/mL can bind Anti-ROR1 Reference Antibody (zilovertamab),EC50=0.00283 µg/mL
  • 产品详情
  • 实验流程
Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
FC, Kinetics, Animal Model
Primary Accession Q01973
Reactivity Human
Clonality Monoclonal
Isotype IgG1
Calculated MW 104283 Da
Additional Information
Target/Specificity ROR1
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Protein Information
Name ROR1
Synonyms NTRKR1
Function Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed:25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443, PubMed:27162350). In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells (PubMed:27162350). Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling (PubMed:36949068).
Cellular Location Membrane; Single- pass type I membrane protein. Cell projection, axon {ECO:0000250|UniProtKB:Q9Z139}
Tissue Location Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

FeedBack

终于等到您。ABCEPTA(百远生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-88856768 tech-china@abcepta.com.


我要评价