NAPSIN A Mouse mAb
NAPSIN A Mouse mAb
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| IHC-P, IHC-F, IF |
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Reactivity | Mouse |
Host | Rabbit |
Clonality | Monoclonal |
Calculated MW | 39 KDa |
Physical State | Liquid |
Immunogen | KLH conjugated synthetic peptide derived from mouse NAPSIN A |
Isotype | IgG1, Kappa |
Purity | affinity purified by Protein A |
Buffer | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Proclin300. |
SUBCELLULAR LOCATION | Secreted (Potential). |
SIMILARITY | Belongs to the peptidase A1 family. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Background Descriptions | Napsin A is an aspartic proteinase that belongs to the peptidase A1 family and plays a role in pneumocyte surfactant processing. It is a 420-amino acid polypeptide consisting of a 24-residue signal peptide, a 40-amino acid propart, the mature enzyme of 336 amino acids, and a C-terminal extension of 18 residues. The mature Napsin A protein contains 3 predicted disulfide bonds, 3 potential N-linked oligosaccharide attachment sites, an RGD motif, a recognition motif for integrin binding, in the C terminus, immediately before a 4-amino acid insert that is unique to aspartic proteinases. Highest levels of Napsin A have been detected in adult lung (type II pneumocytes), fetal lung, and kidney tissues. Napsin A is also expressed at lower levels in adult spleen and at very low levels in peripheral blood leukocytes. Human napsin A shares 72.6% sequence identity with the mouse homolog. |
Target/Specificity | Expressed predominantly in adult lung (type II pneumocytes) and kidney and in fetal lung. Low levels in adult spleen and very low levels in peripheral blood leukocytes. |
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Dilution | IHC-P=1:100-500,IF=1:50-200,IHC-F=1:100-500 |
Format | 0.01M TBS(pH7.4) with 1% BSA, 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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