癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
LRRC50 (19T11) Mouse Monoclonal antibody
LRRC50 (19T11) Mouse Monoclonal antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IF |
|---|---|
| Primary Accession | Q8NEP3 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Calculated MW | 80026 Da |
| Gene ID | 123872 |
|---|---|
| Other Names | Dynein axonemal assembly factor 1, Leucine-rich repeat-containing protein 50, DNAAF1, LRRC50 |
| Dilution | WB~~1:1000 IF~~1:50~200 |
| Storage Conditions | -20℃ |
| Name | DNAAF1 |
|---|---|
| Synonyms | LRRC50 |
| Function | Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli. |
| Cellular Location | Cell projection, cilium. Cytoplasm Cytoplasm, cytoskeleton, spindle pole Note=In HEK293T cells, it is diffusely cytoplasmic and concentrates at the mitotic spindle poles, while in MDCK cells, it localizes in the cilium. In vivo, this protein is probably restricted to the cilium |
| Tissue Location | Mainly expressed in trachea and testis. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene is cilium-specific and is required for the stability of the ciliary architecture. It is involved in the regulation of microtubule-based cilia and actin-based brush border microvilli. Mutations in this gene are associated with primary ciliary dyskinesia-13. COMPLETENESS: complete on the 3' end.
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¥ 1,500.00
Cat# AP93911
