癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Ferritin Heavy Chain (14L9) Rabbit Monoclonal Antibody
Ferritin Heavy Chain (14L9) Rabbit Monoclonal Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC |
|---|---|
| Primary Accession | P09528 |
| Reactivity | Rat, Mouse |
| Clonality | Monoclonal |
| Calculated MW | 21067 Da |
| Gene ID | 14319 |
|---|---|
| Other Names | Ferritin heavy chain, Ferritin H subunit, 1.16.3.1, Ferritin heavy chain, N-terminally processed, Fth1, Fth |
| Dilution | WB~~1:1000 IHC~~1:100~500 |
| Storage Conditions | -20℃ |
| Name | Fth1 |
|---|---|
| Synonyms | Fth |
| Function | Stores iron in a soluble, non-toxic, readily available form (By similarity). Important for iron homeostasis (By similarity). Has ferroxidase activity (By similarity). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity). Also plays a role in delivery of iron to cells (PubMed:19154717). Mediates iron uptake in capsule cells of the developing kidney (PubMed:19154717). Degraded to release iron upon autophagy activation by nutrient starvation (PubMed:25327288). |
| Cellular Location | Cytoplasm. Cytoplasmic vesicle, autophagosome Autolysosome |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Stores iron in a soluble, non-toxic, readily available form
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