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PRPC Rabbit Polyclonal Antibody

PRPC Rabbit Polyclonal Antibody

     
  • 1 - PRPC Rabbit Polyclonal Antibody AP93506
    Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P02810
Reactivity Rat, Human, Mouse
Host Polyclonal, Rabbit,IgG
Clonality Polyclonal
Calculated MW 17015 Da
Additional Information
Gene ID 5554;5555
Other Names Salivary acidic proline-rich phosphoprotein 1/2, Db-s, PRP-1/PRP-2, Parotid acidic protein, Pa, Parotid double-band protein, Parotid isoelectric focusing variant protein, PIF-S, Parotid proline-rich protein 1/2, Pr1/Pr2, Protein C, Salivary acidic proline-rich phosphoprotein 1/2, Salivary acidic proline-rich phosphoprotein 3/4, Db-F, PIF-F, PRP-3/PRP-4, Protein A, Peptide P-C, PRH1
Dilution WB~~1:1000
Storage Conditions-20℃
Protein Information
Name PRH1
Function PRP's act as highly potent inhibitors of crystal growth of calcium phosphates. They provide a protective and reparative environment for dental enamel which is important for the integrity of the teeth.
Cellular Location Secreted.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid and submandibular/sublingual glands. Multiple distinct alleles of this locus including the parotid isoelectric-focusing variant slow (PIF-s), the parotid acidic protein (Pa), and the double band slow (Db-s) isoforms have been characterized. The reference genome encodes the Db-s allele. Certain alleles of this gene are associated with susceptibility to dental caries. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. Co-transcription of this gene with adjacent genes has been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015],

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