癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
CD048 Rabbit Polyclonal Antibody
CD048 Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| IHC, IF |
|---|---|
| Primary Accession | Q5BLP8 |
| Reactivity | Human, Mouse |
| Host | Polyclonal, Rabbit,IgG |
| Clonality | Polyclonal |
| Calculated MW | 10170 Da |
| Gene ID | 401115 |
|---|---|
| Other Names | NELL2-interacting cell ontogeny regulator 1 {ECO:0000312|HGNC:HGNC:34437}, NELL2-interacting cofactor for lumicrine signaling, NICOL1 (HGNC:34437) |
| Dilution | IHC~~1:100~500 IF~~1:50~200 |
| Storage Conditions | -20℃ |
| Name | NICOL1 (HGNC:34437) |
|---|---|
| Function | mRNA-binding protein which interacts with a range of target mRNAs including SERPINE1, ACTA2, CCN2 and COL4A1 and may promote extracellular matrix production. Binds to the 3'-UTR of SERPINE1 mRNA and stabilizes the mRNA, possibly by competing for binding with SERBP1 and preventing SERBP1-mediated mRNA degradation. Also binds to the 3'- UTR of ACTA2. Testis-derived lumicrine factor that triggers epididymal differentiation and sperm maturation. |
| Cellular Location | Secreted {ECO:0000250|UniProtKB:Q3UR78}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q3UR78} Note=Detected in the perinuclear region of fibroblasts {ECO:0000250|UniProtKB:Q3UR78} |
| Tissue Location | Detected in the brain (at protein level) (PubMed:21287218). Also expressed at low levels in the kidney, primarily in tubular epithelial cells (PubMed:38625739) |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
