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RBM19 Rabbit Polyclonal Antibody

RBM19 Rabbit Polyclonal Antibody

     
  • 1 - RBM19 Rabbit Polyclonal Antibody AP93410
    Western blot analysis of lysates from AD293 cells, primary antibody was diluted at 1:1000, 4°over night
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q9Y4C8
Reactivity Human, Mouse
Host Polyclonal, Rabbit,IgG
Clonality Polyclonal
Calculated MW 107332 Da
Additional Information
Gene ID 9904
Other Names Probable RNA-binding protein 19, RNA-binding motif protein 19, RBM19, KIAA0682
Dilution WB~~1:1000
Storage Conditions-20℃
Protein Information
Name RBM19
Synonyms KIAA0682
Function Plays a role in embryo pre-implantation development.
Cellular Location Nucleus, nucleolus. Nucleus, nucleoplasm Cytoplasm. Chromosome. Note=In discrete foci distributed throughout the cytoplasm and nucleoplasm during the 4 to 8 cell stages and the morula stage, but not in the periphery of the nucleolar precursor body (NPB). During blastocyst development, becomes increasingly localized to the nucleolus and less to the cytoplasm. At the late blastocyst stage, localized predominantly in the nucleolus Localized in the nucleolus during interphase and to the perichromosomal sheath during mitosis. Does not colocalize in the cytoplasm with GW182 in P-bodies. May translocate to the nucleolus upon early embryonic development (By similarity). Colocalizes with NPM1 during interphase By late prophase, metaphase, anaphase and telophase, associates with the chromosome periphery. By telophase localizes to NPB.
Tissue Location Expressed in the crypts of Lieberkuhn of the intestine and in intestinal neoplasia (at protein level)
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Apr 2009],

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