PDE4B Antibody

Rabbit mAb

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, FC
Primary Accession	Q07343
Reactivity	Human, Mouse
Clonality	Monoclonal
Other Names	DPDE4; PDE 4B; PDE IVB; PDE32; Pde4b; PDE4B5; PDEIVB; Phosphodiesterase 4B;
Isotype	Rabbit IgG
Host	Rabbit
Calculated MW	83343 Da

Additional Information
Dilution	WB 1:500~1:2000 FC 1:50
Purification	Affinity-chromatography
Immunogen	A synthesized peptide derived from human PDE4B
Description	Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
Storage Condition and Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Protein Information
Name	PDE4B (HGNC:8781)
Synonyms	DPDE4
Function	Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:15260978). May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
Cellular Location	[Isoform PDE4B5]: Cytoplasm. Cell membrane
Tissue Location	Expressed in brain, heart, lung and skeletal muscle (PubMed:17519386). Expressed in white blood cells (PubMed:8392015)