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>   首页   >   产品   >   一抗   >   其他   >   Iba1 Rabbit mAb   

Iba1 Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P
Primary Accession O70200
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 16911 Da
Additional Information
Gene ID 11629
Other Names Aif1
Dilution WB~~1/500-1/1000
IHC-P~~N/A
Format Liquid
Protein Information
Name Aif1
Synonyms Iba1
Function Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Cellular Location Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, phagocytic cup Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Tissue Location Abundantly expressed in the testis, moderately in the spleen and lymph nodes and at low levels in the liver and thymus Detected in macrophages.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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