Mitochondrial Fission 1 Protein Rabbit mAb
- 产品详情
- 实验流程
Application ![]()
| WB, IHC-P, IHC-F, ICC |
---|---|
Primary Accession | Q9Y3D6 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 16938 Da |
Gene ID | 51024 |
---|---|
Other Names | FIS1 |
Dilution | WB~~1/500-1/1000 IHC-P~~N/A IHC-F~~N/A ICC~~N/A |
Format | Liquid |
Name | FIS1 |
---|---|
Synonyms | TTC11 |
Function | Involved in the fragmentation of the mitochondrial network and its perinuclear clustering (PubMed:12783892, PubMed:12861026, PubMed:14996942, PubMed:23283981). Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission (PubMed:12861026, PubMed:16118244, PubMed:23283981, PubMed:23530241, PubMed:24196833). May not be essential for the assembly of functional fission complexes and the subsequent membrane scission event (PubMed:23530241, PubMed:24196833). Also mediates peroxisomal fission (PubMed:16107562). May act when the products of fission are directed toward mitochondrial homeostasis, mitophagy, or apoptosis (PubMed:24196833). Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis (PubMed:12783892). |
Cellular Location | Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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