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>   首页   >   产品   >   一抗   >   精选抗体   >   Mitochondrial Fission 1 Protein Rabbit mAb   

Mitochondrial Fission 1 Protein Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IHC-F, ICC
Primary Accession Q9Y3D6
Reactivity Human
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 16938 Da
Additional Information
Gene ID 51024
Other Names FIS1
Dilution WB~~1/500-1/1000
IHC-P~~N/A
IHC-F~~N/A
ICC~~N/A
Format Liquid
Protein Information
Name FIS1
Synonyms TTC11
Function Involved in the fragmentation of the mitochondrial network and its perinuclear clustering (PubMed:12783892, PubMed:12861026, PubMed:14996942, PubMed:23283981). Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission (PubMed:12861026, PubMed:16118244, PubMed:23283981, PubMed:23530241, PubMed:24196833). May not be essential for the assembly of functional fission complexes and the subsequent membrane scission event (PubMed:23530241, PubMed:24196833). Also mediates peroxisomal fission (PubMed:16107562). May act when the products of fission are directed toward mitochondrial homeostasis, mitophagy, or apoptosis (PubMed:24196833). Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis (PubMed:12783892).
Cellular Location Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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