癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KRT9 Antibody (Center K444)
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P35527 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 62064 Da |
| Antigen Region | 429-456 aa |
| Gene ID | 3857 |
|---|---|
| Other Names | Keratin, type I cytoskeletal 9, Cytokeratin-9, CK-9, Keratin-9, K9, KRT9 |
| Target/Specificity | This KRT9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 429-456 amino acids from the Central region of human KRT9. |
| Dilution | WB~~1:1000 IHC-P~~1:100~500 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KRT9 Antibody (Center K444) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KRT9 |
|---|---|
| Function | May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly. |
| Tissue Location | Expressed in the terminally differentiated epidermis of palms and soles. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
KRT9 is the type I keratin 9, an intermediate filament chain expressed only in the terminally differentiated epidermis of palms and soles. Mutations in this protein cause epidermolytic palmoplantar keratoderma.
REFERENCES
Feng,W., Han,W. Eur J Dermatol 18 (4), 387-390 (2008)
Zhao,J.J., Zhang,Z.H. Int. J. Dermatol. 47 (6), 634-637 (2008)
Torchard,D., Blanchet-Bardon,C. Nat. Genet. 6 (1), 106-110 (1994)
Reis,A., Kuster,W. Hum. Genet. 90 (1-2), 113-116 (1992)
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