癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-CD337 Antibody
Rabbit polyclonal antibody to CD337
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | O14931 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 21593 Da |
| Gene ID | 259197 |
|---|---|
| Other Names | 1C7; LY117; Natural cytotoxicity triggering receptor 3; Activating natural killer receptor p30; Natural killer cell p30-related protein; NK-p30; NKp30; CD337 |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD337. The exact sequence is proprietary. |
| Dilution | WB~~WB (1/500 - 1/1000) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | NCR3 (HGNC:19077) |
|---|---|
| Synonyms | 1C7, LY117 |
| Function | Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Selectively expressed by all resting and activated NK cells and weakly expressed in spleen. {ECO:0000269|PubMed:10562324, ECO:0000269|Ref.2} |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD337. The exact sequence is proprietary.
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¥ 1,500.00
Cat# AP61340
