癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-Peripherin Antibody
Rabbit polyclonal antibody to Peripherin
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- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | P41219 |
| Reactivity | Human, Rat, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 53651 Da |
| Gene ID | 5630 |
|---|---|
| Other Names | NEF4; PRPH1; Peripherin; Neurofilament 4 |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Peripherin. The exact sequence is proprietary. |
| Dilution | WB~~WB (1/500 - 1/1000) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | PRPH |
|---|---|
| Synonyms | NEF4, PRPH1 |
| Function | Class-III neuronal intermediate filament protein (By similarity). May form an independent structural network without the involvement of other neurofilaments or may cooperate with the neuronal intermediate filament proteins NEFL, NEFH, NEFM and INA to form a filamentous network (PubMed:15322088, PubMed:15446584). Assembly of the neuronal intermediate filaments may be regulated by RAB7A (By similarity). Plays a role in the development of unmyelinated sensory neurons (By similarity). May be involved in axon elongation and axon regeneration after injury (By similarity). Inhibits neurite extension in type II spiral ganglion neurons in the cochlea (By similarity). |
| Cellular Location | Cytoplasm, cytoskeleton. Cell projection, axon {ECO:0000250|UniProtKB:P15331}. Perikaryon {ECO:0000250|UniProtKB:P15331} |
| Tissue Location | Expressed in the neurons of the outer hair cells in the organ of Corti and to a lesser extent in type I spiral ganglion cells. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Peripherin. The exact sequence is proprietary.
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¥ 1,500.00
Cat# AP59677
