癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
BTBD6 Rabbit pAb
BTBD6 Rabbit pAb
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Application 
| WB |
|---|---|
| Primary Accession | Q96KE9 |
| Reactivity | Rat, Rabbit |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 58776 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human BTBD6 |
| Epitope Specificity | 131-240/485 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cytoplasm, P-body (By similarity).Note=Cytoplasmic bodies (By similarity) |
| SIMILARITY | Contains 1 BTB (POZ) domain. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The function of BTB/POZ domain containing protein 6 is not known. The BTB/POZ domain is an evolutionarily conserved protein-protein interaction domain often found in developmentally regulated transcription factors. Many additional conserved motifs have been found in association with BTB/POZ domain, including kelch repeats, zinc finger domains, FYVE fingers and ankyrin repeats. BTB/POZ domain containing protein 6 may be involved in neuronal development and muscle formation. |
| Gene ID | 90135 |
|---|---|
| Other Names | BTB/POZ domain-containing protein 6, Lens BTB domain protein, BTBD6 (HGNC:19897), BDPL |
| Target/Specificity | Expressed in lens. |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Name | BTBD6 (HGNC:19897) |
|---|---|
| Synonyms | BDPL |
| Function | Adapter protein for the cul3 E3 ubiquitin-protein ligase complex (By similarity). Involved in late neuronal development and muscle formation (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q2LE78}. Note=Found in punctated bodies in the cytoplasm {ECO:0000250|UniProtKB:Q2LE78} |
| Tissue Location | Expressed in lens.. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The function of BTB/POZ domain containing protein 6 is not known. The BTB/POZ domain is an evolutionarily conserved protein-protein interaction domain often found in developmentally regulated transcription factors. Many additional conserved motifs have been found in association with BTB/POZ domain, including kelch repeats, zinc finger domains, FYVE fingers and ankyrin repeats. BTB/POZ domain containing protein 6 may be involved in neuronal development and muscle formation.
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