ADSSL1 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

ADSSL1 Antibody (N-term) (Cat. #AP5873a) western blot analysis in mouse bladder tissue lysates (15ug/lane).This demonstrates the ADSSL1 antibody detected ADSSL1 protein (arrow).
ADSSL1 antibody (N-term) (Cat. #AP5873a) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ADSSL1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P, E
Primary Accession	Q8N142
Other Accession	A4Z6H0, P28650, A5PJR4, NP_689541.1, NP_954634.1
Reactivity	Human, Mouse
Predicted	Pig, Bovine
Host	Rabbit
Clonality	Polyclonal
Isotype	Rabbit IgG
Calculated MW	50208 Da
Antigen Region	96-123 aa

Additional Information
Gene ID	122622
Other Names	Adenylosuccinate synthetase isozyme 1 {ECO:0000255\|HAMAP-Rule:MF_03126}, AMPSase 1 {ECO:0000255\|HAMAP-Rule:MF_03126}, AdSS 1 {ECO:0000255\|HAMAP-Rule:MF_03126}, 6344 {ECO:0000255\|HAMAP-Rule:MF_03126}, Adenylosuccinate synthetase, basic isozyme {ECO:0000255\|HAMAP-Rule:MF_03126}, Adenylosuccinate synthetase, muscle isozyme {ECO:0000255\|HAMAP-Rule:MF_03126}, M-type adenylosuccinate synthetase {ECO:0000255\|HAMAP-Rule:MF_03126}, IMP--aspartate ligase 1 {ECO:0000255\|HAMAP-Rule:MF_03126}, ADSSL1 {ECO:0000255\|HAMAP-Rule:MF_03126}
Target/Specificity	This ADSSL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-123 amino acids from the N-terminal region of human ADSSL1.
Dilution	WB~~1:1000 IHC-P~~1:100~500 E~~Use at an assay dependent concentration.
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions	ADSSL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.

Protein Information
Name	ADSS1 (HGNC:20093)
Function	Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
Cellular Location	Cytoplasm {ECO:0000255\|HAMAP-Rule:MF_03126, ECO:0000269\|PubMed:15786719}
Tissue Location	Predominantly expressed in skeletal muscle and heart, as well as in several hematopoietic cell lines and solid tumors

Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

Application Protocols

Provided below are standard protocols that you may find useful for product applications.