Anti-Sugen Kinase 269 Antibody

Western blot analysis of Sugen Kinase 269 expression in HEK293T (A), LO2 (B) whole cell lysates.

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB
Primary Accession	Q9H792
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Calculated MW	193106 Da

Additional Information
Gene ID	79834
Other Names	KIAA2002; Pseudopodium-enriched atypical kinase 1; Sugen kinase 269; Tyrosine-protein kinase SgK269
Target/Specificity	Recognizes endogenous levels of Sugen Kinase 269 protein.
Dilution	WB~~1/500 - 1/1000
Format	Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
Storage	Store at -20 °C.Stable for 12 months from date of receipt

Protein Information
Name	PEAK1
Synonyms	KIAA2002
Function	Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics (PubMed:20534451, PubMed:23105102, PubMed:35687021). Acts as a scaffold for mediating EGFR signaling (PubMed:23846654).
Cellular Location	Cytoplasm, cytoskeleton. Cell junction, focal adhesion Note=Colocalizes with F-actin in serum-rich medium (PubMed:20534451) Actin colocalization is reduced during serum starvation (PubMed:20534451).