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>   首页   >   产品   >   一抗   >   神经科学   >   BRN3C Antibody   

BRN3C Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q15319
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 37052 Da
Additional Information
Gene ID 5459
Other Names POU domain, class 4, transcription factor 3, Brain-specific homeobox/POU domain protein 3C, Brain-3C, Brn-3C, POU4F3, BRN3C
Dilution WB~~1:1000
Format 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name POU4F3
Synonyms BRN3C
Function Acts as a transcriptional activator (PubMed:18228599). Acts by binding to sequences related to the consensus octamer motif 5'- ATGCAAAT-3' in the regulatory regions of its target genes (PubMed:18228599). Involved in the auditory system development, required for terminal differentiation of hair cells in the inner ear (By similarity).
Cellular Location Nucleus. Cytoplasm Note=Preferentially localized in the nucleus
Tissue Location Brain. Seems to be specific to the retina.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

May play a role in determining or maintaining the identities of a small subset of visual system neurons.

REFERENCES

Xiang M.,et al.J. Neurosci. 15:4762-4785(1995).
Vahava O.,et al.Science 279:1950-1954(1998).
Collin R.W.J.,et al.Hum. Mutat. 29:545-554(2008).

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