BRN3C Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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- 实验流程
- 背景知识
Application ![]()
| WB |
---|---|
Primary Accession | Q15319 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 37052 Da |
Gene ID | 5459 |
---|---|
Other Names | POU domain, class 4, transcription factor 3, Brain-specific homeobox/POU domain protein 3C, Brain-3C, Brn-3C, POU4F3, BRN3C |
Dilution | WB~~1:1000 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | POU4F3 |
---|---|
Synonyms | BRN3C |
Function | Acts as a transcriptional activator (PubMed:18228599). Acts by binding to sequences related to the consensus octamer motif 5'- ATGCAAAT-3' in the regulatory regions of its target genes (PubMed:18228599). Involved in the auditory system development, required for terminal differentiation of hair cells in the inner ear (By similarity). |
Cellular Location | Nucleus. Cytoplasm Note=Preferentially localized in the nucleus |
Tissue Location | Brain. Seems to be specific to the retina. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
May play a role in determining or maintaining the identities of a small subset of visual system neurons.
REFERENCES
Xiang M.,et al.J. Neurosci. 15:4762-4785(1995).
Vahava O.,et al.Science 279:1950-1954(1998).
Collin R.W.J.,et al.Hum. Mutat. 29:545-554(2008).

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¥ 1,500.00
Cat# AP51700