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ECE2 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 14 - ECE2 Antibody (Center) AP20460c
    Immunohistochemical analysis of paraffin-embedded H. prostate section using ECE2 Antibody (Center)(Cat#AP20460C). AP20460C was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
  • 1 - ECE2 Antibody (Center) AP20460c
    ECE2 Antibody (Center) (Cat. #AP20460c) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the ECE2 antibody detected the ECE2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession O60344
Other Accession Q80Z60, Q10711
Reactivity Human, Mouse
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Antigen Region 551-579 aa
Additional Information
Other Names Endothelin-converting enzyme 2, ECE-2, Methyltransferase-like region, 211-, Endothelin-converting enzyme 2 region, ECE2, KIAA0604
Target/Specificity This ECE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-579 amino acids from the Central region of human ECE2.
Dilution WB~~1:1000
IHC-P~~1:100~500
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsECE2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.

REFERENCES

Lorenzo M.-N., et al. Biochim. Biophys. Acta 1522:46-52(2001).
Funke-Kaiser H., et al. Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
Nagase T., et al. DNA Res. 5:31-39(1998).
Clark H.F., et al. Genome Res. 13:2265-2270(2003).
Muzny D.M., et al. Nature 440:1194-1198(2006).

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