PRKCSH antibody - N-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application ![]()
| WB |
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Primary Accession | P14314 |
Other Accession | NM_002743, NP_002734 |
Reactivity | Human, Mouse, Rat, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine |
Predicted | Human, Mouse, Rat, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 59425 Da |
Gene ID | 5589 |
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Alias Symbol | AGE-R2, G19P1, PCLD, PLD1 |
Other Names | Glucosidase 2 subunit beta, 80K-H protein, Glucosidase II subunit beta, Protein kinase C substrate 60.1 kDa protein heavy chain, PKCSH, PRKCSH, G19P1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-PRKCSH antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | PRKCSH antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PRKCSH {ECO:0000303|PubMed:28375157, ECO:0000312|HGNC:HGNC:9411} |
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Function | Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (PubMed:10929008). Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (By similarity). |
Cellular Location | Endoplasmic reticulum {ECO:0000255|PROSITE- ProRule:PRU10138, ECO:0000305|PubMed:10929008} |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Sakai K.,et al.Genomics 5:309-315(1989).
Ophoff R.A.,et al.Eur. J. Hum. Genet. 4:321-328(1996).
Pelletier M.F.,et al.Glycobiology 10:815-827(2000).
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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