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为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Lap3 antibody - N-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q9CPY7 |
| Other Accession | NM_024434, NP_077754 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Rabbit, Zebrafish, Chicken, Dog, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 56141 Da |
| Gene ID | 66988 |
|---|---|
| Alias Symbol | 2410015L10Rik, AA410100, Lap, Lapep, Pep-7, Pep-S, Pep7, Peps, LAP-3 |
| Other Names | Cytosol aminopeptidase, 3.4.11.1, Leucine aminopeptidase 3, LAP-3, Leucyl aminopeptidase, Proline aminopeptidase, 3.4.11.5, Prolyl aminopeptidase, Lap3, Lapep |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Lap3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Lap3 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Lap3 {ECO:0000312|MGI:MGI:1914238} |
|---|---|
| Synonyms | Lapep |
| Function | Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S- conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q68FS4}. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Zhuang D.Z.,et al.Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
Lubec G.,et al.Submitted (APR-2007) to UniProtKB.
Villen J.,et al.Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
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