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Wnt-3a

     
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Product Information
Species Human
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1 EU per µg by the LAL method.
Biological Activity Wnt-3a hFc Chimera, Human (Cat.No.: Z03815) can induce Topflash reporter activity in HEK293T human embryonic kidney cells.
Expression System HEK293
Theoretical Molecular Weight 58.50 kDa.
Formulation Lyophilized from 0.22 µm filtered solution in PBS, pH 7.4.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 µg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the lyophilized product remains stable up to 6 months at -20 °C or below as supplied from date of receipt.-80°C for 3 months after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Additional Information
Target Background Wnt-3a activates the canonical Wnt signaling pathway and is expressed in the dorsal midline region, playing a crucial role in spinal cord development. Additionally, it regulates autophagy, apoptosis, neuron regeneration, neurogenic inflammation, and axon regeneration. Wnt-3a promotes the beta-catenin/Tcf pathway, which can induce tumors and lead to cancer in specific cell populations. Moreover, it is widely used in cytokine for organoid construction.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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