Spike Protein S1

Product Information
Primary Accession	P0DTC2
Species	SARS-CoV-2
Sequence	Gln14-Arg685 (E484K,K417T,N501Y)
Purity	> 95% as analyzed by SDS-PAGE
Endotoxin Level	< 0.2 EU/ µg of protein by gel clotting method
Biological Activity	This protein is validated to bind with human ACE2 in functional ELISA assay.
Expression System	CHO
Theoretical Molecular Weight	75.7 kDa
Formulation	Supplied as a solution in PBS, pH 7.4.
Storage & Stability	Upon receiving, this product remains stable for up to 6 months at -20°C or below. Please avoid repeated freeze-thaw cycles.

Additional Information
Other Names	Spike glycoprotein {ECO:0000255\|HAMAP-Rule:MF_04099}, S glycoprotein {ECO:0000255\|HAMAP-Rule:MF_04099}, E2 {ECO:0000255\|HAMAP-Rule:MF_04099}, Peplomer protein {ECO:0000255\|HAMAP-Rule:MF_04099}, Spike protein S1 {ECO:0000255\|HAMAP-Rule:MF_04099}, Spike protein S2 {ECO:0000255\|HAMAP-Rule:MF_04099}, Spike protein S2' {ECO:0000255\|HAMAP-Rule:MF_04099}, S {ECO:0000255\|HAMAP-Rule:MF_04099}
Target Background	SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. Lineage P.1, also known as the Brazil(ian) variant is one of the variants of SARS-CoV-2. This variant has 17 amino acid changes, ten of which are in its spike protein, including these three designated to be of particular concern: N501Y, E484K and K417T. SARS-CoV-2 Spike protein (S1, E484K, K417T, N501Y, His Tag) carries a polyhistidine tag at the C-terminus.