癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
S100-A6
- 产品详情
- 实验流程
| Primary Accession | NP_055439.1 |
|---|---|
| Species | Human |
| Sequence | MHHHHHHMAC PLDQAIGLLV AIFHKYSGRE GDKHTLSKKE LKELIQKELT IGSKLQDAEI ARLMEDLDRN KDQEVNFQEY VTFLGALALI YNEALKG |
| Purity | > 95% as analyzed by SDS-PAGE. |
| Endotoxin Level | < 1 EU/ µg, determined by LAL method. |
| Formulation | Lyophilized after extensive dialysis against 50mM Tris-HCl, 100mM NaCI, 0.5mM PMSF, 1mM TCEP, pH8.0. |
| Reconstitution | Reconstituted in ddH2O at 200 µg/ml. |
| Target Background | S100 calcium-binding protein A6 (S100A6) is a small calcium binding protein with 2 EF-hand structures and belongs to the S100 family. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 proteins include at least 25 members which are located as a cluster on chromosome 1q21. S100A6 protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. Recombinant S100 calcium-binding protein A6 (S100A6) with His tag produced in E. coli is a single chain containing 97 amino acids with molecular mass of 11.1 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at . |
|---|
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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