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>   首页   >   产品   >   一抗   >   精选抗体   >   内参抗体   >   YY1 Antibody (monoclonal) (M04)   

YY1 Antibody (monoclonal) (M04)

Mouse monoclonal antibody raised against a partial recombinant YY1.

     
  • 1 - YY1 Antibody (monoclonal) (M04) AT4565a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • 1 - YY1 Antibody (monoclonal) (M04) AT4565a
    YY1 monoclonal antibody (M04), clone 2C5 Western Blot analysis of YY1 expression in Hela S3 NE ( (Cat # AT4565a )
  • 2 - YY1 Antibody (monoclonal) (M04) AT4565a
    Immunoperoxidase of monoclonal antibody to YY1 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 7 ug/ml]
  • 3 - YY1 Antibody (monoclonal) (M04) AT4565a
    Immunofluorescence of monoclonal antibody to YY1 on HeLa cell. [antibody concentration 10 ug/ml]
  • 10 - YY1 Antibody (monoclonal) (M04) AT4565a
    Detection limit for recombinant GST tagged YY1 is approximately 0.03ng/ml as a capture antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC, IF, E
Primary Accession P25490
Other Accession NM_003403
Reactivity Human
Host mouse
Clonality monoclonal
Isotype IgG1 Kappa
Clone Names 2C5
Calculated MW 44713 Da
Additional Information
Gene ID 7528
Other Names Transcriptional repressor protein YY1, Delta transcription factor, INO80 complex subunit S, NF-E1, Yin and yang 1, YY-1, YY1, INO80S
Target/Specificity YY1 (NP_003394, 221 a.a. ~ 320 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
IHC~~1:100~500
IF~~1:50~200
E~~N/A
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsYY1 Antibody (monoclonal) (M04) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.

REFERENCES

CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy. de Nigris F, et al. Proc Natl Acad Sci U S A, 2010 Aug 10. PMID 20660740.Transcription factor YY1 interacts with retroviral integrases and facilitates integration of moloney murine leukemia virus cDNA into the host chromosomes. Inayoshi Y, et al. J Virol, 2010 Aug. PMID 20519390.Repressors NFI and NFY participate in organ-specific regulation of von Willebrand factor promoter activity in transgenic mice. Nassiri M, et al. Arterioscler Thromb Vasc Biol, 2010 Jul. PMID 20431063.Identification of Yin Yang 1-interacting partners at -1026C/A in the human iNOS promoter. Li W, et al. Arch Biochem Biophys, 2010 Jun 15. PMID 20430007.Identification of a Smad4/YY1-recognized and BMP2-responsive transcriptional regulatory module in the promoter of mouse GABA transporter subtype I (Gat1) gene. Yao M, et al. J Neurosci, 2010 Mar 17. PMID 20237276.

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