癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SGTA Antibody (monoclonal) (M06)
Mouse monoclonal antibody raised against a partial recombinant SGTA.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IF, IP, E |
|---|---|
| Primary Accession | O43765 |
| Other Accession | NM_003021 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 2E12 |
| Calculated MW | 34063 Da |
| Gene ID | 6449 |
|---|---|
| Other Names | Small glutamine-rich tetratricopeptide repeat-containing protein alpha, Alpha-SGT, Vpu-binding protein, UBP, SGTA, SGT, SGT1 |
| Target/Specificity | SGTA (NP_003012.1, 42 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 IP~~N/A E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | SGTA Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function.
REFERENCES
Family-based analysis of candidate genes for polycystic ovary syndrome. Ewens KG, et al. J Clin Endocrinol Metab, 2010 May. PMID 20200332.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.Structural and functional characterization of human SGT and its interaction with Vpu of the human immunodeficiency virus type 1. Dutta S, et al. Biochemistry, 2008 Sep 23. PMID 18759457.Expression, purification and preliminary crystallographic analysis of recombinant human small glutamine-rich tetratricopeptide-repeat protein. Dutta S, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2008 Jul 1. PMID 18607086.Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA), a candidate gene for polycystic ovary syndrome. Goodarzi MO, et al. Hum Reprod, 2008 May. PMID 18332089.
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