癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
NSEP1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant YBX1.
- 产品详情
- 实验流程
Application 
| WB, IF, E |
|---|---|
| Primary Accession | P67809 |
| Other Accession | NM_004559 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 4F12 |
| Calculated MW | 35924 Da |
| Gene ID | 4904 |
|---|---|
| Other Names | Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A, CBF-A, DNA-binding protein B, DBPB, Enhancer factor I subunit A, EFI-A, Y-box transcription factor, Y-box-binding protein 1, YB-1, YBX1, NSEP1, YB1 |
| Target/Specificity | YBX1 (NP_004550, 51 a.a. ~ 139 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | NSEP1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
YB-1 alters MT1-MMP trafficking and stimulates MCF-7 breast tumor invasion and metastasis. Lovett DH, et al. Biochem Biophys Res Commun, 2010 Jul 30. PMID 20599698.Y-box binding protein-1 is a novel molecular target for tumor vessels. Takahashi M, et al. Cancer Sci, 2010 Jun. PMID 20398058.Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance. To K, et al. Cancer Res, 2010 Apr 1. PMID 20332234.Upregulated c-myc expression in multiple myeloma by internal ribosome entry results from increased interactions with and expression of PTB-1 and YB-1. Cobbold LC, et al. Oncogene, 2010 May 13. PMID 20190818.[Effect of YB-1 gene knockdown on human leukemia cell line K562/A02] Xu WL, et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2009 Aug. PMID 20017303.
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
