癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
LDB1 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a partial recombinant LDB1.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q86U70 |
| Other Accession | NM_003893 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 4G8 |
| Calculated MW | 46533 Da |
| Gene ID | 8861 |
|---|---|
| Other Names | LIM domain-binding protein 1, LDB-1, Carboxyl-terminal LIM domain-binding protein 2, CLIM-2, LIM domain-binding factor CLIM2, hLdb1, Nuclear LIM interactor, LDB1, CLIM2 |
| Target/Specificity | LDB1 (NP_003884, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | LDB1 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Transcription intermediary factor 1gamma decreases protein expression of the transcriptional cofactor, LIM-domain-binding 1. Howard PW, et al. Biochem Biophys Res Commun, 2010 Jun 4. PMID 20447379.Regulation of LIM-domain-binding 1 protein expression by ubiquitination of Lys134. Howard PW, et al. Biochem J, 2010 Jul 1. PMID 20423330.Regulation of estrogen-dependent transcription by the LIM cofactors CLIM and RLIM in breast cancer. Johnsen SA, et al. Cancer Res, 2009 Jan 1. PMID 19117995.Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes. Bhati M, et al. EMBO J, 2008 Jul 23. PMID 18583962.Assembly of the oncogenic DNA-binding complex LMO2-Ldb1-TAL1-E12. Ryan DP, et al. Proteins, 2008 Mar. PMID 17910069.
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