癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KHDRBS1 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a partial recombinant KHDRBS1.
- 产品详情
- 实验流程
Application 
| WB, IHC, IF, E |
|---|---|
| Primary Accession | Q07666 |
| Other Accession | BC000717 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 1A4 |
| Calculated MW | 48227 Da |
| Gene ID | 10657 |
|---|---|
| Other Names | KH domain-containing, RNA-binding, signal transduction-associated protein 1, GAP-associated tyrosine phosphoprotein p62, Src-associated in mitosis 68 kDa protein, Sam68, p21 Ras GTPase-activating protein-associated p62, p68, KHDRBS1 (HGNC:18116) |
| Target/Specificity | KHDRBS1 (AAH00717, 176 a.a. ~ 275 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IHC~~1:100~500 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | KHDRBS1 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy. Pedrotti S, et al. EMBO J, 2010 Apr 7. PMID 20186123.Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients. Sellier C, et al. EMBO J, 2010 Apr 7. PMID 20186122.Alternative splicing of the cyclin D1 proto-oncogene is regulated by the RNA-binding protein Sam68. Paronetto MP, et al. Cancer Res, 2010 Jan 1. PMID 20028857.Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 Nuclear Bodies. Rajan P, et al. BMC Cell Biol, 2009 Nov 13. PMID 19912651.Expression and cytoplasmic localization of SAM68 is a significant and independent prognostic marker for renal cell carcinoma. Zhang Z, et al. Cancer Epidemiol Biomarkers Prev, 2009 Oct. PMID 19755649.
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