癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
FZD3 Antibody (monoclonal) (M09)
Mouse monoclonal antibody raised against a partial recombinant FZD3.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IF, E |
|---|---|
| Primary Accession | Q9NPG1 |
| Other Accession | NM_017412 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 2H5 |
| Calculated MW | 76263 Da |
| Gene ID | 7976 |
|---|---|
| Other Names | Frizzled-3, Fz-3, hFz3, FZD3 |
| Target/Specificity | FZD3 (NP_059108, 55 a.a. ~ 157 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | FZD3 Antibody (monoclonal) (M09) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.
REFERENCES
Pathway-based approaches to imaging genetics association studies: Wnt signaling, GSK3beta substrates and major depression. Inkster B, et al. Neuroimage, 2010 Nov 15. PMID 20219685.Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer. Kawano Y, et al. Br J Cancer, 2009 Apr 7. PMID 19277043.Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence. Greg?rio SP, et al. Psychiatry Res, 2009 Jan 30. PMID 19054571.Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells. Wang HX, et al. Mol Hum Reprod, 2009 Jan. PMID 19038973.The Frizzled 3 gene is associated with methamphetamine psychosis in the Japanese population. Kishimoto M, et al. Behav Brain Funct, 2008 Aug 15. PMID 18702828.
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
