癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
EBF3 Antibody (monoclonal) (M06)
Mouse monoclonal antibody raised against a partial recombinant EBF3.
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q9H4W6 |
| Other Accession | NM_001005463 |
| Reactivity | Human, Rat |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 1G3 |
| Calculated MW | 64864 Da |
| Gene ID | 253738 |
|---|---|
| Other Names | Transcription factor COE3, Early B-cell factor 3, EBF-3, Olf-1/EBF-like 2, O/E-2, OE-2, EBF3, COE3 |
| Target/Specificity | EBF3 (NP_001005463, 381 a.a. ~ 480 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | EBF3 Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
HPV status-independent association of alcohol and tobacco exposure or prior radiation therapy with promoter methylation of FUSSEL18, EBF3, IRX1, and SEPT9, but not SLC5A8, in head and neck squamous cell carcinomas. Bennett KL, et al. Genes Chromosomes Cancer, 2010 Apr. PMID 20029986.[Construction of eukaryotic expression vector for EBF3 and EGFP fusion protein and its expression in HepG2 cells] Mao LP, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 2008 Oct. PMID 18845077.Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma. Bennett KL, et al. Cancer Res, 2008 Jun 15. PMID 18559491.Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931.An EBF3-mediated transcriptional program that induces cell cycle arrest and apoptosis. Zhao LY, et al. Cancer Res, 2006 Oct 1. PMID 17018599.
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