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>   首页   >   产品   >   一抗   >   细胞生物学   >   CSE1L Antibody (monoclonal) (M01)   

CSE1L Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant CSE1L.

     
  • 1 - CSE1L Antibody (monoclonal) (M01) AT1650a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • 1 - CSE1L Antibody (monoclonal) (M01) AT1650a
    CSE1L monoclonal antibody (M01), clone 2B7 Western Blot analysis of CSE1L expression in Hela S3 NE ( (Cat # AT1650a )
  • 3 - CSE1L Antibody (monoclonal) (M01) AT1650a
    Immunofluorescence of monoclonal antibody to CSE1L on HeLa cell. [antibody concentration 25 ug/ml]
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF
Primary Accession P55060
Other Accession NM_001316
Reactivity Human
Host mouse
Clonality monoclonal
Isotype IgG1 kappa
Clone Names 2B7
Calculated MW 110417 Da
Additional Information
Gene ID 1434
Other Names Exportin-2, Exp2, Cellular apoptosis susceptibility protein, Chromosome segregation 1-like protein, Importin-alpha re-exporter, CSE1L, CAS, XPO2
Target/Specificity CSE1L (NP_001307, 872 a.a. ~ 971 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
IF~~1:50~200
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCSE1L Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.

REFERENCES

1.Interdependency of Cystathione ?^-Lyase and Cystathione ?]-Synthase in Hydrogen Sulfide-Induced Blood Pressure Regulation in Rats.Roy A, Khan AH, Islam MT, Prieto MC, Majid DS.Am J Hypertens. 2011 Aug 25. doi: 10.1038/ajh.2011.149. [Epub ahead of print]

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