癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
ASNA1 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant ASNA1.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | O43681 |
| Other Accession | NM_004317 |
| Reactivity | Human, Rat |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 5A3 |
| Calculated MW | 38793 Da |
| Gene ID | 439 |
|---|---|
| Other Names | ATPase ASNA1 {ECO:0000255|HAMAP-Rule:MF_03112}, 36-- {ECO:0000255|HAMAP-Rule:MF_03112}, Arsenical pump-driving ATPase {ECO:0000255|HAMAP-Rule:MF_03112}, Arsenite-stimulated ATPase {ECO:0000255|HAMAP-Rule:MF_03112}, Transmembrane domain recognition complex 40 kDa ATPase subunit, hARSA-I, hASNA-I, ASNA1 {ECO:0000255|HAMAP-Rule:MF_03112}, ARSA, TRC40 |
| Target/Specificity | ASNA1 (NP_004308, 239 a.a. ~ 348 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | ASNA1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
ASNA1 is the human homolog of the bacterial arsA gene. In E. coli, ArsA ATPase is the catalytic component of a multisubunit oxyanion pump that is responsible for resistance to arsenicals and antimonials.
REFERENCES
Asna1/TRC40-mediated membrane insertion of tail-anchored proteins. Favaloro V, et al. J Cell Sci, 2010 May 1. PMID 20375064.Increased sensitivity to platinating agents and arsenite in human ovarian cancer by downregulation of ASNA1. Hemmingsson O, et al. Oncol Rep, 2009 Oct. PMID 19724867.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.A precursor-specific role for Hsp40/Hsc70 during tail-anchored protein integration at the endoplasmic reticulum. Rabu C, et al. J Biol Chem, 2008 Oct 10. PMID 18667436.Identification of a targeting factor for posttranslational membrane protein insertion into the ER. Stefanovic S, et al. Cell, 2007 Mar 23. PMID 17382883.
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
