癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
ANAPC11 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant ANAPC11.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NYG5 |
| Other Accession | BC000607 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 1B4-1A4 |
| Calculated MW | 9841 Da |
| Gene ID | 51529 |
|---|---|
| Other Names | Anaphase-promoting complex subunit 11, APC11, Cyclosome subunit 11, Hepatocellular carcinoma-associated RING finger protein, ANAPC11 |
| Target/Specificity | ANAPC11 (AAH00607, 1 a.a. ~ 54 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | ANAPC11 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression. W?sch R, et al. Oncogene, 2010 Jan 7. PMID 19826416.The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction. Nilsson J, et al. Nat Cell Biol, 2008 Dec. PMID 18997788.Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex. Jin L, et al. Cell, 2008 May 16. PMID 18485873.Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. Wang AG, et al. Biochem Biophys Res Commun, 2006 Jul 7. PMID 16712791.Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. Dube P, et al. Mol Cell, 2005 Dec 22. PMID 16364912.
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