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>   首页   >   产品   >   一抗   >   基因重组   >   Anti-Complement C5aR1 Reference Antibody (G2 patent anti-C5aR)   

Anti-Complement C5aR1 Reference Antibody (G2 patent anti-C5aR)

Recombinant Antibody

     
  • 1 - Anti-Complement C5aR1 Reference Antibody (G2 patent anti-C5aR) APR10844
    Anti-Complement C5aR1 Reference Antibody (G2 patent anti-C5aR) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
  • 1 - Anti-Complement C5aR1 Reference Antibody (G2 patent anti-C5aR) APR10844
    The purity of Anti-Complement C5aR1 Reference Antibody (G2 patent anti-C5aR)is more than 95% ,determined by SEC-HPLC.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
FC, Kinetics, Animal Model
Primary Accession P21730
Reactivity Human
Clonality Monoclonal
Isotype IgG1
Calculated MW 39336 Da
Additional Information
Target/Specificity Complement C5aR1
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Protein Information
Name C5AR1
Synonyms C5AR, C5R1
Function Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:10636859, PubMed:15153520, PubMed:1847994, PubMed:29300009, PubMed:7622471, PubMed:8182049, PubMed:9553099). The ligand interacts with at least two sites on the receptor: a high- affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:7622471, PubMed:8182049, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
Cellular Location Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle. Note=Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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