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>   首页   >   产品   >   一抗   >   基因重组   >   Anti-GCGR Reference Antibody (volagidemab)   

Anti-GCGR Reference Antibody (volagidemab)

Recombinant Antibody

     
  • 1 - Anti-GCGR Reference Antibody (volagidemab) APR10709
    Anti-GCGR Reference Antibody (volagidemab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
  • 1 - Anti-GCGR Reference Antibody (volagidemab) APR10709
    The purity of Anti-GCGR Reference Antibody (volagidemab)is more than 98.43% ,determined by SEC-HPLC.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
FC, Kinetics, Animal Model
Primary Accession P47871
Reactivity Human, Mouse
Clonality Monoclonal
Isotype IgG2SA
Calculated MW 54009 Da
Additional Information
Target/Specificity GCGR
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Protein Information
Name GCGR
Function G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein. Note=Is rapidly internalized after ligand-binding
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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