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>   首页   >   产品   >   一抗   >   基因重组   >   Anti-AOC3 / VAP1 Reference Antibody (timolumab)   

Anti-AOC3 / VAP1 Reference Antibody (timolumab)

Recombinant Antibody

     
  • 1 - Anti-AOC3 / VAP1 Reference Antibody (timolumab) APR10628
    Anti-AOC3 / VAP1 Reference Antibody (timolumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%
  • 1 - Anti-AOC3 / VAP1 Reference Antibody (timolumab) APR10628
    The purity of Anti-AOC3 / VAP1 Reference Antibody (timolumab)is more than 95% ,determined by SEC-HPLC.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
FC, Kinetics, Animal Model
Primary Accession Q16853
Reactivity Mouse, Rabbit
Clonality Monoclonal
Isotype IgG4SP
Calculated MW 84622 Da
Additional Information
Target/Specificity AOC3 / VAP1
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Protein Information
Name AOC3 (HGNC:550)
Synonyms VAP1
Function Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia (PubMed:19588076, PubMed:24304424, PubMed:9653080). Has a preference for the primary monoamines methylamine and benzylamine (PubMed:19588076, PubMed:9653080). Could also act on 2-phenylethylamine but much less efficiently (PubMed:19588076). At endothelial cells surface can also function as a cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion (PubMed:9254657, PubMed:9653080).
Cellular Location Cell membrane; Single-pass type II membrane protein
Tissue Location Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis. Isoform 2 seems to be the predominant transcript in fetal kidneys, fetal cartilage and fetal tonsils. The highest relative expression of isoform 2 occurs in skeletal muscle, heart, pancreas, kidney, and lung
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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