Anti-STAB1 Reference Antibody (bexmarilimab)

Recombinant Antibody

Anti-STAB1 Reference Antibody (bexmarilimab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
The purity of Anti-STAB1 Reference Antibody (bexmarilimab)is more than 100% ,determined by SEC-HPLC.
Immobilized human STAB His at 2 µg/mL can bind Anti-STAB1 Reference Antibody (bexmarilimab)，EC50=0.06461 µg/mL
Human STAB A4 HEK293 cells were stained with Anti-STAB1 Reference Antibody (bexmarilimab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC273=0.2417 µg/mL

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	FC, Kinetics, Animal Model
Primary Accession	Q9NY15
Reactivity	Human
Clonality	Monoclonal
Isotype	IgG4
Calculated MW	275482 Da

Additional Information
Target/Specificity	STAB1
Endotoxin	< 0.001EU/ µg,determined by LAL method.
Conjugation	Unconjugated
Expression system	CHO Cell
Format	Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.

Protein Information
Name	STAB1
Synonyms	FEEL1, KIAA0246
Function	Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system.
Cellular Location	Membrane; Single-pass type I membrane protein
Tissue Location	High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells

Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

Application Protocols

Provided below are standard protocols that you may find useful for product applications.