RPS19 Recombinant Rabbit mAb
RPS19 Recombinant Rabbit mAb
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, IHC-P, IHC-F, IF, IP |
---|---|
Reactivity | Human |
Host | Rabbit |
Clonality | Recombinant |
Calculated MW | 16 KDa |
Physical State | Liquid |
Immunogen | A synthesized peptide derived from human RPS19 |
Epitope Specificity | 100-145/145 |
Isotype | IgG |
Purity | affinity purified by Protein A |
Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
SUBCELLULAR LOCATION | Cytoplasm ; Nucleus, nucleolus |
SIMILARITY | Belongs to the eukaryotic ribosomal protein eS19 family. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Background Descriptions | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
Target/Specificity | Higher level expression is seen in the colon carcinoma tissue than normal colon tissue. |
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Dilution | WB=1:500-1000,IHC-P=1:100-500,IP=1:20-50,IF=1:100-500,IHC-F=1:100-500 |
Format | 0.01M TBS(pH7.4) with 1% BSA, 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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