CD8 Recombinant Rabbit mAb
CD8 Recombinant Rabbit mAb
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| IHC-P, IHC-F, IF |
---|---|
Reactivity | Human |
Host | Rabbit |
Clonality | Recombinant |
Calculated MW | 26 KDa |
Physical State | Liquid |
Immunogen | KLH conjugated synthetic peptide derived from human CD8 |
Isotype | IgG |
Purity | affinity purified by Protein A |
Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
SUBCELLULAR LOCATION | Membrane; Single-pass type I membrane protein. |
SIMILARITY | Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
SUBUNIT | In general heterodimer of an alpha and a beta chain linked by two disulfide bonds. Can also form homodimers. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Background Descriptions | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] |
Target/Specificity | Most prominently found in the gastrointestinal tract, skin, lung, and brain but not in liver. |
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Dilution | IHC-P=1:50-300,IHC-F=1:50-300,IF=1:50-300 |
Format | 0.01M TBS(pH7.4) with 1% BSA, 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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