CD43 Recombinant Mouse mAb
CD43 Recombinant Mouse mAb
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| IF, ICC |
---|---|
Host | Rabbit |
Clonality | Recombinant |
Physical State | Liquid |
Isotype | IgG1, Kappa |
Purity | affinity purified by Protein G |
Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
SUBCELLULAR LOCATION | Membrane; Single-pass type I membrane protein. |
SUBUNIT | Interacts with HIPK2 via the cytoplasmic domain. Interacts with RDX. |
Post-translational modifications | Glycosylated; has a high content of sialic acid and O-linked carbohydrate structures. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Background Descriptions | This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017] |
Target/Specificity | Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas. |
---|---|
Dilution | ICC/IF=1:50,Flow-Cyt=1:50-1:100 |
Format | 0.01M TBS(pH7.4) with 1% BSA, 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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