CD89 Recombinant Mouse mAb
CD89 Recombinant Mouse mAb
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- 实验流程
- 背景知识
Application ![]()
| IF, ICC |
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Host | Rabbit |
Clonality | Recombinant |
Physical State | Liquid |
Isotype | IgG1, Kappa |
Purity | affinity purified by Protein G |
Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
SUBCELLULAR LOCATION | Isoform A.1: Cell membrane; Single-pass type I membrane protein. Isoform A.2: Cell membrane; Single-pass type I membrane protein.Isoform A.3: Cell membrane; Single-pass type I membrane protein.Isoform B: Secreted.Isoform B-delta-S2: Secreted. |
SIMILARITY | Contains 2 Ig-like C2-type (immunoglobulin-like) domains. |
SUBUNIT | Associates with the Fc epsilon RI gamma 2 receptor inducing tyrosine phosphorylation of gamma 2. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Background Descriptions | Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. Tissue specificity; Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces. |
Target/Specificity | Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces. |
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Dilution | ICC/IF=1:50,Flow-Cyt=1:50-1:100 |
Format | 0.01M TBS(pH7.4) with 1% BSA, 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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