癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
PCDHB8 (9N15) Mouse Monoclonal antibody
PCDHB8 (9N15) Mouse Monoclonal antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | Q9UN66 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Calculated MW | 87591 Da |
| Gene ID | 56128 |
|---|---|
| Other Names | Protocadherin beta-8, PCDH-beta-8, Protocadherin-3I, PCDHB8 (HGNC:8693), PCDH3I |
| Dilution | WB~~1:1000 |
| Storage Conditions | -20℃ |
| Name | PCDHB8 (HGNC:8693) |
|---|---|
| Synonyms | PCDH3I |
| Function | Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination. Thereby, it is involved in the establishment and maintenance of specific neuronal connections in the brain. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q91XZ2}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q91XZ2} |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008]
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