癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Tissue Factor (13K19) Rabbit Monoclonal Antibody
Tissue Factor (13K19) Rabbit Monoclonal Antibody
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- 实验流程
- 背景知识
Application 
| WB, IP |
|---|---|
| Primary Accession | P20352 |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Calculated MW | 32935 Da |
| Gene ID | 14066 |
|---|---|
| Other Names | Tissue factor, TF, Coagulation factor III, CD142, F3, Cf-3, Cf3 |
| Dilution | WB~~1:1000 IP~~N/A |
| Storage Conditions | -20℃ |
| Name | F3 |
|---|---|
| Synonyms | Cf-3, Cf3 |
| Function | Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:P13726}; Single- pass type I membrane protein {ECO:0000250|UniProtKB:P13726} |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a membrane-bound glycoprotein that forms the primary physiological initiator of the blood coagulation process following vascular damage. The encoded protein binds to coagulation factor VIIa and the ensuing complex catalyzes the proteolytic activation of coagulation factors IX and X. Mice lacking encoded protein die in utero resulting from massive hemorrhaging in both extraembryonic and embryonic vessels. A severe deficiency of the encoded protein in mice results in impaired uterine homeostasis, shorter life spans due to spontaneous fatal hemorrhages and cardiac fibrosis. [provided by RefSeq, Aug 2015]
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