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Nestin (7M5) Rabbit Monoclonal Antibody

Nestin (7M5) Rabbit Monoclonal Antibody

     
  • 1 - Nestin (7M5) Rabbit Monoclonal Antibody AP93715
    Western blot analysis of extracts from Neuro-2a cells using AP93715 at 1:1000.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC
Primary Accession Q6P5H2, P21263
Reactivity Rat, Mouse
Clonality Monoclonal
Calculated MW 207124 Da
Additional Information
Gene ID 18008
Dilution WB~~1:1000
IHC~~1:100~500
Storage Conditions-20℃
Protein Information
Name Nes
Function Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division (By similarity). Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Predicted to enable CCR5 chemokine receptor binding activity. Acts upstream of or within cell projection morphogenesis; negative regulation of neuron apoptotic process; and nervous system development. Located in cytoplasm and intermediate filament. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; foregut-midgut junction; and metanephros. Orthologous to human NES (nestin). [provided by Alliance of Genome Resources, Apr 2022]

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