Nestin (7M5) Rabbit Monoclonal Antibody
Nestin (7M5) Rabbit Monoclonal Antibody
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Application ![]()
| WB, IHC |
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Primary Accession | Q6P5H2, P21263 |
Reactivity | Rat, Mouse |
Clonality | Monoclonal |
Calculated MW | 207124 Da |
Gene ID | 18008 |
---|---|
Dilution | WB~~1:1000 IHC~~1:100~500 |
Storage Conditions | -20℃ |
Name | Nes |
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Function | Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division (By similarity). Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Predicted to enable CCR5 chemokine receptor binding activity. Acts upstream of or within cell projection morphogenesis; negative regulation of neuron apoptotic process; and nervous system development. Located in cytoplasm and intermediate filament. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; foregut-midgut junction; and metanephros. Orthologous to human NES (nestin). [provided by Alliance of Genome Resources, Apr 2022]

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