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KR104 Rabbit Polyclonal Antibody

KR104 Rabbit Polyclonal Antibody

     
  • 1 - KR104 Rabbit Polyclonal Antibody AP93512
    Western blot analysis of lysates from THP-1 cells, primary antibody was diluted at 1:1000, 4°over night
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P60372
Reactivity Rat, Human, Mouse
Host Polyclonal, Rabbit,IgG
Clonality Polyclonal
Calculated MW 40475 Da
Additional Information
Gene ID 386672
Other Names Keratin-associated protein 10-4, High sulfur keratin-associated protein 10.4, Keratin-associated protein 10.4, Keratin-associated protein 18-4, Keratin-associated protein 18.4, KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Dilution WB~~1:1000
Storage Conditions-20℃
Protein Information
Name KRTAP10-4
Synonyms KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4,
Function In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Tissue Location Restricted to hair root, not detected in any other tissues
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

This is an intronless gene located in a cluster of related genes on the q arm of chromosome 21. The proteins encoded by these genes form disulfide bonds with cysteine residues in hair keratins, thereby contributing to the structure and stability of hair fibers. [provided by RefSeq, Apr 2014],

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